Dimethylaminoethanol (DMAE)

What Is Dimethylaminoethanol (DMAE)?

Dimethylaminoethanol (DMAE) is a naturally produced amine in the brain, and you can also find high levels in certain seafood. DMAE increases levels of the neurotransmitter acetylcholine, leading to improved mood and concentration and better sleep patterns.*

Benefits of Dimethylaminoethanol (DMAE)

• Improves memory*
• Increases sense of well-being*
• Improves sleep patterns*
• Increases alertness and concentration*

What You Need to Know About Dimethylaminoethanol (DMAE)

Dimethylaminoethanol, or DMAE, is a natural brain chemical in high concentrations in certain seafood. Many users experience increased well-being when taking DMAE, along with improved alertness, better sleep quality, and enhanced focus and concentration.

DMAE does all this by increasing acetylcholine formation. It's also won accolades as an anti-aging supplement because it reduces the build-up of an "age pigment" known as beta-amyloid that impairs cognition.

DMAE also protects nerve cells from oxidation and various "beauty creams" include the compound in their formulations to tighten sagging skin.

Research on Dimethylaminoethanol (DMAE)

1. Dimpfel W et al. Efficacy of dimethylaminoethanol (DMAE) containing vitamin-mineral drug combination on EEG patterns in the presence of different emotional states. Eur J Med Res. 2003 May 30;8(5):183-91. ABSTRACT: The psychophysiological model of provoking different emotional states by watching film excerpts with various emotional contents was used to characterize drug action in 80 subjects (male/female=50%) with threshold emotional disturbance within a randomized, group-parallel, double-blind, placebo-controlled study. Analyzing the brain's electrical reaction during presentation of 5 videoclips of 7 min duration followed by 3 minutes pause revealed a content specific representation of topographical frequency changes. This procedure was repeated after 6 and 12 weeks of daily intake of a vitamin-mineral drug combination containing dimethylaminoethanol (DMAE) (Vitagerin Geistlich N) or placebo. Subjects taking the active drug for 3 months developed significant less theta and alpha1 power in sensomotoric areas of the cortex. The grade of change and statistical significance was dependend on the content of the excerpt, but the pattern of changes in general remained the same. Since decreases in theta and alpha1 electrical power have been associated with increased vigilance and attention, subjects taking the drug combination obviously were more active and felt better. - Analysis of the emotional change in mood profile as induced by the TV session was achieved by completing two different quenstionaires (POMS and Bf-S). Both scores revealed a better mood for the active drug group thus corroborating the results from EEG analysis. Therefore the vitamine-mineral drug combination containing DMAE can be interpreted to induce a psychophysiological state of better feeling of wellbeing on both levels of analysis mood and electrical pattern of brain activity in subjects suffering from borderline emotional disturbance.
2. Danysz A et al. The influence of 2-dimethylaminethanol (DMAE) on the mental and physical efficiency in man. Act Nerv Super (Praha). 1967 Nov;9(4):417.
3. Rugginenti A. Effects of dimethylaminoethanol acetyl glutamate on the attentive capacity of a group of soccer players. Arch Maragliano Patol Clin. 1974 Jul-Dec;30(2):189-98.
4. Sabourin H et al. Dimethylaminoethanol and personality disorders of the young adult. Electro-clinical correlations. Ann Med Psychol (Paris). 1966 Apr;124(4):579-84.
5. Boutillier H et al. Apropos of some cases of personality and behavior disorders in children treated by dimethylaminoethanol. Gaz med fr. 1963 oct 10;70:2929-33.
6. Knobel M et al.2-Dimethylaminoethanol in behavior disorders of childhood. Sem Med. 1961 Sep 18;119:939-44.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.