What Is Acetyl-L-Carnitine?
Acetyl-L-carnitine is a naturally occurring amino acid that increases the neurotransmitters norepinephrine and serotonin, which play essential roles in boosting mood and optimizing brain function. It fuels mitochondria increasing cellular energy. It directly enhances neural transmission by stimulating synapses or blocking post-synaptic inhibition. And it synergizes other nootropics, potentiating the overall effects of the formula. Using acetyl-L-carnitine feels like it increases your electrical "wattage," so you burn brighter and longer.*
Benefits of Acetyl-L-Carnitine
- Improves mood, social interaction, and verbal fluency*
- Increases energy production in the mitochondria, boosting physical and mental energy for several hours*
- Increases mental processing speed, learning rate, attention span, short-term and long-term memory, and facial recognition*
- Increases glucose levels in the brain*
- Stimulates brain cells prompting them to grow more connections to other neurons*
What You Need to Know About Acetyl-L-Carnitine
Acetyl-L-carnitine (ALCAR) is a naturally occurring amino acid that's essential for the proper functioning of mitochondria. While your body produces it naturally, it sometimes struggles to produce enough.
This is why people who take extra ALCAR often experience incredible benefits such as increased energy, enhanced cognition, and improved focus. Acetyl-L-carnitine is so effective that it's injected intravenously to emergency room patients suffering from reduced blood flow to the brain.
Products Containing Acetyl-L-Carnitine
Sorry, there are no products in this collection.
Research on Acetyl-L-Carnitine
- Abbasi SH et al. Acetyl-L-carnitine as an adjunctive therapy in the treatment of attention-deficit/hyperactivity disorder in children and adolescents: a placebo-controlled trial. Child Psychiatry Hum Dev. 2011 Jun;42(3):367-75.
- Inazu M et al. Physiological Functions of Carnitine and Carnitine Transporters in the Central Nervous System. Japanese Journal of Psychopharmacology. 2008 Jun;28(3):113-20.
- Iossa S et al. Acetyl-L-carnitine supplementation differently influences nutrient partitioning, serum leptin concentration and skeletal muscle mitochondrial respiration in young and old rats. J Nutr. 2002;132:636-42.
- Malaguarnera M et al. Acetyl-L-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathy. Scand J Gastroenterol. 2011;46(6):750-759.
- Malaguarnera M et al. Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue. Arch Gerontol Geriatr. 2008;46(2):181-190.
- Malaguarnera M et al. Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Am J Clin Nutr. 2011;93(4):799-808.
- Malaguarnera M et al. Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial. Metab Brain Dis. 2011;26(4):281-289.
- Evans AM et al. Pharmacokinetics of L-carnitine. Clin Pharmacokinet. 2003;42:941-67.
- Veronese N et al. Acetyl-L-carnitine supplementation and the treatment of depressive symptoms: a systematic review and meta-analysis. Psychosom Med. Feb/Mar 2018;80(2):154-159. doi: 10.1097/PSY.0000000000000537.
- Cristofano A et al. Serum levels of acyl-carnitines along the continuum from normal to Alzheimer's dementia. PLoS One. 2016 May 19;11(5):e0155694. doi: 10.1371/journal.pone.0155694. eCollection 2016.
- Thal LJ et al. A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease. Neurology. 1996 Sep;47(3):705-11. doi: 10.1212/wnl.47.3.705.
- Thal LJ et al. A 1-year controlled trial of acetyl-l-carnitine in early-onset AD. Neurology. 2000 Sep 26;55(6):805-10. doi: 10.1212/wnl.55.6.805.
- Brooks JO 3rd et al. Acetyl L-carnitine slows decline in younger patients with Alzheimer's disease: a reanalysis of a double-blind, placebo-controlled study using the trilinear approach. Int Psychogeriatr. 1998 Jun;10(2):193-203. doi: 10.1017/s1041610298005304.
- Hudson S et al. Acetyl-L-carnitine for dementia. Cochrane Database Syst Rev. 2003(2):Cd003158.
- Montgomery SA et al. Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease. Int Clin Psychopharmacol. 2003;18(2):61-71.