The Alpha Male® formula contains three of the most potent testosterone-boosting compounds found anywhere on the planet.* In fact, you could call Alpha Male® the ultimate male "elixir."* So, if you're interested in maximizing T, reducing body fat, and feeling super energized in the gym, Alpha Male® Maximum Strength Pro-Testosterone formula is perfect for you.*
Biotest has three T-boosting compounds that are the benchmarks for the sports-supplement industry:*
| Alpha Male® Formula | 2-Tablet Serving |
|---|---|
| Bulgarian Tribulus terrestris (root) extract 50:1 | 500 mg |
| Malaysian Eurycoma longifolia (aerial) extract 100:1 | 100 mg |
| Forskolin Carbonate | 20 mg |
Each of these compounds is super concentrated to achieve maximum potency. Furthermore, Biotest evaluates every batch of raw material to ensure that each finished bottle performs at the highest possible standard.
Although in some aspects similar, these compounds achieve their T-boosting effects through different mechanisms.
Bulgarian Tribulus
Tribulus acts as a Luteinizing-hormone secretagogue (LHS). In other words, it causes the release of Luteinizing hormone, which in turn signals the testes to produce more testosterone.* And of all the T-boosting compounds on the market, Tribulus is the most powerful.*
The brutal reality is, most Tribulus products on the market are either completely inactive or inferior herbal substitutes that are mistakenly spiked with protodioscin. Either way, you get the same result — nothing!
You can't simply take Chinese, or Indian, or "German" plant material and spike it with protodioscin to make real testosterone-boosting Tribulus. It's a cheap and ineffective imitation and it's dishonest.
Genuine full-spectrum Tribulus that boosts testosterone is only found in Bulgaria and contains many powerful compounds vital for producing ideal results. All compounds have to be present in "fingerprinted" full-spectrum ratios to achieve the maximum effect.*
Biotest Tribulus contains the most potent, full-spectrum extraction of real Bulgarian Tribulus. Each of the active compounds is present in the required amounts for maximum performance.
Malaysian Eurycoma
In addition to stimulating LH to increase testosterone levels, authentic Malaysian Eurycoma longifolia selectively controls DHEA to testosterone, prevents testosterone from aromatizing to estrogen, and releases bound testosterone.
Eurycoma also increases erectile strength through a mechanism independent of testosterone that, when combined with its other attributes, qualifies it as an herb that's as close to being an aphrodisiac as there is.
One way to trigger erections is through nitric oxide. Another is by blocking a chemical in the body known as rho kinases (ROCK). When you inhibit ROCK, you get bigger and stronger erections, and Eurycoma was found in a recent study to specifically inhibit ROCK-2, an action which researchers believe might explain the herb's "aphrodisiac" effect.
Of course, the strong erections attained through Eurycoma use might also be the result of synergism between elevated testosterone, ROCK-2 inhibition, and perhaps some other yet to be discovered mechanisms.
Forskolin Carbonate (Carbolin 19® brand)
Forskolin carbonate is a carbonate ester of a naturally occurring diterpene called forskolin. Don't confuse this material with the herbal extract Coleus forskohlii. Forskolin carbonate is a highly pure single compound that extends forskolin's duration of action from four hours to 12 hours and substantially improves its bioavailability.*
A study on forskolin shows that it significantly increases lean body mass and reduces fat mass compared to a placebo. Here are the results:
Forskolin Study
| Study Parameters | Details |
|---|---|
| Subjects | 30 men |
| Controls | Randomized, double-blind placebo |
| Duration | 12 weeks |
| Forskolin dose | 50 mg/day |
| Study Results | Forskolin | Placebo | Difference |
|---|---|---|---|
| Lean mass gains | 8.2 lb | 3.8 lb | 4.4 lb |
| Fat loss | -10 lb | -1.1 lb | -8.9 lb |
The version of forskolin used in the study is much weaker than forskolin carbonate. In addition to being more potent, forskolin carbonate has a longer active life and a substantially greater bioavailability.*
Maximum Strength Pro-Testosterone Formula
It's a fact, the Alpha Male® formula contains the ultimate T-boosting stack. Each of its key ingredients is the most potent and most pure found anywhere.
References
- Ezzat SM et al. Rho-Kinase II Inhibitory Potential of Eurycoma longifolia New Isolate for the Management of Erectile Dysfunction. Evidence Based Complementary and Alternative Medicine, 15 May 2019.
Background: Eurycoma longifolia Jack (Fam.: Simaroubaceae), known as Tongkat Ali (TA), has been known as a symbol of virility and sexual power. The aim of the study was to screen E. longifolia aqueous extract (AE) and isolates for ROCK-II inhibition.
Results: The AE (1-10 μg/ml) showed a significant inhibition for ROCK-II activity (62.8-81%) at P < 0.001 with an IC50 (651.1 ± 32.9 ng/ml) compared to Y-27632 ([(+)-(R)-trans-4-(1-aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride]) (68.15-89.9 %) at same concentrations with an IC50 (192 ± 8.37 ng/ml). Chromatographic purification of the aqueous extract (AE) allowed the isolation of eight compounds; stigmasterol T1, trans-coniferyl aldehyde T2, scopoletin T3, eurycomalactone T4, 6α- hydroxyeurycomalactone T5, eurycomanone T6, eurycomanol T7, and eurycomanol-2-O-β-D-glucopyranoside T8. This is the first report for the isolation of T1 and T3 from E. longifolia and for the isolation of T2 from genus Eurycoma. The isolates (at 10 μg/ml) exhibited maximum inhibition % of ROCK-II 82.1 ± 0.63 (T2), 78.3 ± 0.38 (T6), 77.1 ± 0.11 (T3), 76.2 ± 3.53 (T4), 74.5 ± 1.27 (T5), 74.1 ± 2.97 (T7), 71.4 ± 2.54 (T8), and 60.3 ± 0.14 (T1), where the newly isolated compound trans-coniferyl aldehyde T2 showed the highest inhibitory activity among the tested isolated compounds and even higher than the total extract AE. The standard Y-27632 (10 μg/ml) showed 89.9 ± 0.42 % inhibition for ROCK-II activity when compared to control at P < 0.0001.
Conclusion: The traditional use of E. longifolia as aphrodisiac and for male sexual disorders might be in part due to the ROCK-II inhibitory potential. - Low BS et al. Standardized quassinoid-rich Eurycoma longifolia extract improved spermatogenesis and fertility in male rats via the hypothalamic-pituitary-gonadal axis. J Ethnopharmacol. 2013 Feb 13;145(3):706-14.
Ethnopharmacological Relevance: Eurycoma longifolia Jack, a small Simaroubaceae tree, known locally as 'Tongkat Ali' is popularly used as a sexual tonic in traditional medicine for aphrodisiac activity and improvement of fertility and male libido.
Aim of the Study: To investigate the effects of the standardized bioactive fraction of E. longifolia and its chemical constituents on the male fertility and the mechanisms of action involved.
Material and Methods: The powdered roots of E. longifolia were extracted separately with methanol and water. The organic extract upon further fractionation on HP 20 resin and elution with the methanol/water mixture afforded four fractions (F1-F4). These fractions, together with the crude aqueous (W) and organic extracts were standardized following their respective major quassinoid content and profile. The effects of the fractions on the rat spermatogenesis were compared with that of the aqueous extract (W) to determine the bioactive fraction. The effects of the bioactive fraction on the sperm count and quality, the histological morphometric changes on the spermatogenesis cycle, fertility and hormonal changes of plasma testosterone, luteinizing hormone (LH), follicle stimulating hormone (FSH) and estrogen in the animals upon oral administration were determined. The effects of the bioactive quassinoids on the testosterone release from the isolated testicular interstitial cells rich in Leydig cells, were also described.
Results: The male rats orally administered with 25mg/kg of F2 and 250mg/kg of W, significantly increased the sperm concentration when compared with that of the control animals (P< 0.05). High performance liquid chromatography analysis revealed that 25mg/kg of F2 and 250mg/kg of W were almost similar in concentration of eurycomanone, the major and most potent quassinoid. Microscopic morphometrical analysis of the rat testis following treatment with F2, showed significant increase in the number of spermatocytes and round spermatids at Stage VII of the spermatogenesis cycle when compared to that of the control (P< 0.05). The estimated spermatozoa production rate and the number of Leydig cells were also elevated (P< 0.001). The fertility index, fecundity index and the pup litter size delivered from the females after mating with the males treated with F2 were increased. The plasma testosterone level of the animals given 25mg/kg of F2 orally was significantly different at day-26 (p< 0.05) and day-52 (P< 0.01) from those of control but was not different at day-104. The testicular testosterone also peaked in the animals treated with 25mg/kg F2 and was higher than that in the plasma. The plasma LH and FSH levels of the rats treated with 25mg/kg of F2 were higher than those of the control (P< 0.001). In contrast, the plasma estrogen level was significantly lower than that of the untreated control. Amongst the isolated quassinoids of F2, eurycomanone and 13α(21)-dihydroeurycomaone significantly increased the testosterone level from the Leydig cells of the testicular interstitial cells cultured in vitro (P< 0.05).
Conclusion: The standardised extract F2 of E. longifolia and its major quassinoids especially eurycomanone improved the rat spermatogenesis by affecting the hypothalamic-pituitary-gonadal axis and the potential efficacy may be worthy of further investigation. - Muhamad AS et al. Eurycoma longifolia Jack: Medicinal properties and its effects on endurance exercise performance. Asian Journal of Exercise & Sport Science, 2009, Vol. 6 (No. 1).
Abstract: This review article discusses the medicinal properties of a herbal plant, Eurycoma longifolia Jack, and its possible ergogenic effect on endurance exercise performance. To date, herbs or plant products that have been investigated as ergogenic aids for enhancing endurance performance are caffeine, ginseng, mahuang, ephedrine and related alkaloids. Eurycoma longifolia Jack is one of the herbs found in Malaysia. It is commonly known as ‘Tongkat Ali’ in Malaysia and as ‘Pasak Bumi’ in Indonesia. It is also referred to as ‘Malaysian ginseng’ since it is well-known among various ethnic groups in Malaysia for treating various diseases and enhancing health. Eurycoma longifolia Jack is a tall, slender shrubby tree found on sandy soil. It belongs to the Simaroubaceae family and grows wildly in Southeast Asian countries, i.e. Malaysia, Indonesia, Thailand, and Myanmar. To our knowledge, studies on Eurycoma longifolia Jack as an ergogenic aid for enhancing endurance performance is lacking. Thus, this review article highlights the available studies on its purported medicinal properties as well as studies that have been carried out to investigate its effects on physiological responses and endurance exercise performance. - Rehman SU et al. Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology." Molecules, 2016, 21(3), 331.
Abstract: Eurycoma longifolia Jack (known as tongkat ali), a popular traditional herbal medicine, is a flowering plant of the family Simaroubaceae, native to Indonesia, Malaysia, Vietnam and also Cambodia, Myanmar, Laos and Thailand. E. longifolia, is one of the well-known folk medicines for aphrodisiac effects as well as intermittent fever (malaria) in Asia. Decoctions of E. longifolia leaves are used for washing itches, while its fruits are used in curing dysentery. Its bark is mostly used as a vermifuge, while the taproots are used to treat high blood pressure, and the root bark is used for the treatment of diarrhea and fever. Mostly, the roots extract of E. longifolia are used as folk medicine for sexual dysfunction, aging, malaria, cancer, diabetes, anxiety, aches, constipation, exercise recovery, fever, increased energy, increased strength, leukemia, osteoporosis, stress, syphilis and glandular swelling. The roots are also used as an aphrodisiac, antibiotic, appetite stimulant and health supplement. The plant is reported to be rich in various classes of bioactive compounds such as quassinoids, canthin-6-one alkaloids, β-carboline alkaloids, triterpene tirucallane type, squalene derivatives and biphenyl neolignan, eurycolactone, laurycolactone, and eurycomalactone, and bioactive steroids. Among these phytoconstituents, quassinoids account for a major portion of the E. longifolia root phytochemicals. An acute toxicity study has found that the oral Lethal Dose 50 (LD50) of the alcoholic extract of E. longifolia in mice is between 1500-2000 mg/kg, while the oral LD50 of the aqueous extract form is more than 3000 mg/kg. Liver and renal function tests showed no adverse changes at normal daily dose and chronic use of E. longifolia. Based on established literature on health benefits of E. longifolia, it is important to focus attention on its more active constituents and the constituents' identification, determination, further development and most importantly, the standardization. Besides the available data, more evidence is required regarding its therapeutic efficacy and safety, so it can be considered a rich herbal source of new drug candidates. It is very important to conserve this valuable medicinal plant for the health benefit of future generations. - Solomon MC et al. In vivo effects of Eurycoma longifolia Jack (Tongkat Ali) extract on reproductive functions in the rat. Andrologia. 2014 May;46(4):339-48.
Abstract: An aqueous extract of Eurycoma longifolia (Tongkat Ali; TA) roots is traditionally used to enhance male sexuality. Because previous studies are limited to only few sperm parameters or testosterone concentration, this study investigated the in vivo effects of TA on body and organ weight as well as functional sperm parameters in terms of safety and efficacy in the management of male infertility. Forty-two male rats were divided into a control, low-dose (200 mg kg(-1) BW) and high-dose (800 mg kg(-1) BW) group (n = 14). Rats were force-fed for 14 days and then sacrificed. Total body and organ weights of the prostate, testes, epididymides, gastrocnemius muscle and the omentum were recorded. Moreover, testosterone concentration, sperm concentration, motility, velocity, vitality, acrosome reaction and mitochondrial membrane potential (MMP) were assessed. Whilst TA decreased BW by 5.7% (P = 0.0276) and omentum fat by 31.9% (P = 0.0496), no changes in organ weights were found for the prostate, testes and epididymides. Testosterone concentration increased by 30.2% (P = 0.0544). Muscle weight also increased, yet not significantly. Whilst sperm concentration, total and progressive motility and vitality increased significantly, MMP improved markedly (P = 0.0765) by 25.1%. Because no detrimental effect could be observed, TA appears safe for possible treatment of male infertility and ageing male problems. - Solomon MC et al. In vivo effects of Eurycoma longifolia Jack (Tongkat Ali) extract on reproductive functions in the rat. Andrologia. 2014 May;46(4):339-48.
Abstract: An aqueous extract of Eurycoma longifolia (Tongkat Ali; TA) roots is traditionally used to enhance male sexuality. Because previous studies are limited to only few sperm parameters or testosterone concentration, this study investigated the in vivo effects of TA on body and organ weight as well as functional sperm parameters in terms of safety and efficacy in the management of male infertility. Forty-two male rats were divided into a control, low-dose (200 mg kg(-1) BW) and high-dose (800 mg kg(-1) BW) group (n = 14). Rats were force-fed for 14 days and then sacrificed. Total body and organ weights of the prostate, testes, epididymides, gastrocnemius muscle and the omentum were recorded. Moreover, testosterone concentration, sperm concentration, motility, velocity, vitality, acrosome reaction and mitochondrial membrane potential (MMP) were assessed. Whilst TA decreased BW by 5.7% (P = 0.0276) and omentum fat by 31.9% (P = 0.0496), no changes in organ weights were found for the prostate, testes and epididymides. Testosterone concentration increased by 30.2% (P = 0.0544). Muscle weight also increased, yet not significantly. Whilst sperm concentration, total and progressive motility and vitality increased significantly, MMP improved markedly (P = 0.0765) by 25.1%. Because no detrimental effect could be observed, TA appears safe for possible treatment of male infertility and ageing male problems. - Godard MP et al. Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men. Obesity Research. August 2005. DOI: 10.1038/oby.2005.162.
Objective: This study examined the effect of forskolin on body composition, testosterone, metabolic rate, and blood pressure in overweight and obese (BMI > or = 26 kg/m(2)) men.
Research methods and procedure: Thirty subjects (forskolin, n = 15; placebo, n = 15) were studied in a randomized, double-blind, placebo-controlled study for 12 weeks.
Results: Forskolin was shown to elicit favorable changes in body composition by significantly decreasing body fat percentage (BF%) and fat mass (FM) as determined by DXA compared with the placebo group (p < or = 0.05). Additionally, forskolin administration resulted in a change in bone mass for the 12-week trial compared with the placebo group (p < or = 0.05). There was a trend toward a significant increase for lean body mass in the forskolin group compared with the placebo group (p = 0.097). Serum free testosterone levels were significantly increased in the forskolin group compared with the placebo group (p < or = 0.05). The actual change in serum total testosterone concentration was not significantly different among groups, but it increased 16.77 +/- 33.77% in the forskolin group compared with a decrease of 1.08 +/- 18.35% in the placebo group.
Discussion: Oral ingestion of forskolin (250 mg of 10% forskolin extract twice a day) for a 12-week period was shown to favorably alter body composition while concurrently increasing bone mass and serum free testosterone levels in overweight and obese men. The results indicate that forskolin is a possible therapeutic agent for the management and treatment of obesity.
Eurycoma longifolia References
Forskolin References
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Disclaimer: Individual results may vary.