Leucine Structured Peptides
250% Greater Muscle Growth!
Structured Peptides are absorbed faster, utilized better, and produce 250 percent greater muscle growth than free-form amino acids.
BIOTEST® Leucine and BCAA Structured Peptides are produced from peptide enhanced whey-protein isolate, utilizing a three-step process:
- Whey-protein isolate is hydrolyzed into very small peptide forms using a combination of selective enzymes (aminopeptidases and proteases) to break apart targeted leucine peptide and BCAA-peptide bonds.
- Afterward, small peptide formations are extracted from the hydrolyzed whey by passing the mixture through a series of filters, ending with nanofiltration.
- Next, the nano-mixture undergoes a final reaction phase to further enhance its total leucine and BCAA content.
The end result is a highly refined mixture of leucine and BCAA di- and tripeptides that provides the body with the greatest effects from leucine/ BCAA supplementation.
Di- and Tripeptide Science
- Unlike regular (free-form) amino acids, the uptake of di- and tripeptides is achieved through a very specific, high-capacity intestinal transporter (PEPT-1), which can lead to a larger and more rapid spike in blood levels of these crucial anabolic signals.
- Most of the anabolic effects of protein are actually the result of a single amino acid – leucine. Only slight elevations in all of the other essential amino acids are necessary for leucine to spark (and maintain) increases in muscle protein synthesis.
- Leucine is the amino-acid "trigger" by which skeletal muscle accrues protein. Specifically, the muscle-building effects of leucine are due to a cascade of cellular reactions including the activation of the mammalian target of rapamycin (mTOR), upregulation of ribosomal protein S6 kinase (S6K1) activity, enhancement of eukaryotic initiation factor-4E binding protein (eIF4E-BP1) phosphorylation, and the association of eukaryotic initiation factor (eIF)4E with eIF4G. These effects have been shown to occur both in vitro and in humans.
- Estimates of dietary requirements for leucine range from 1 g to 12 g daily. The amount of leucine necessary to optimize performance and muscle growth is unknown, but recent research in humans points to a plateau effect (at least on muscle protein synthesis) occurring around 3.5 grams per meal.
- As we get older, muscles become less sensitive to the anabolic effects of insulin, protein, and amino acids (including leucine). As a result, peri-workout nutrition becomes more important to maximize our overall health and performance.
- Leucine oxidation by muscle can be reduced by co-ingesting a high-quality carbohydrate, an effect that in theory should increase the anabolic signal to muscle growth.
- Although theoretical at this point in time, key leucine di- and tripeptides may turn out to provide extraordinary muscle-building benefits.
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