P-Well Prostate Support
P-Well Prostate Support
P-Well Prostate Support
P-Well Prostate Support
P-Well Prostate Support
P-Well Prostate Support
P-Well Prostate Support

P-Well Prostate Support

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The P-Well™ supplement is different from most formulas in that you won't have to take it on faith that it's working. It'll show you it's working by how it positively changes your life with stronger urine streams and more efficient bladder emptying. You could also enjoy a better sex life with more blood flow into the penis. Lastly, and perhaps most importantly, P-Well™ supports the overall health and function of the all-too-vulnerable prostate.*

Prostate Support*

  • Promotes healthy prostate size and function*
  • Helps manage oxidative stress and inflammation*
  • Supports healthy urination and bladder emptying*
  • Helps protect prostate cells*
  • Promotes healthy hormone metabolism in the prostate*
  • Helps maintain already healthy PSA levels*

Sexual Vascular Health*

  • Promotes better blood flow to the penis*
  • Helps improve sperm quality and motility*

Urinary Tract Health*

  • Supports healthy urinary flow*
  • Helps protect urinary tract surface and lining*

Supports Healthy Urination & Bladder Emptying*

P-Well Prostate Support Benefit

Promotes Healthy
Prostate Size & Function*

P-Well Prostate Support Benefit

Supports Healthy
Urination & Emptying*

P-Well Prostate Support Benefit

Promotes Better Blood
Flow to Urinary Tract*

  1. Vidlar A et al. The effectiveness of dried cranberries ( Vaccinium macrocarpon) in men with lower urinary tract symptoms. Brit J Nutr, 2010 Oct;104(8):118-9. Summary: The objective of this study was to evaluate the efficacy and tolerability of cranberry (Vaccinium macrocarpon) powder in men at risk of prostate disease with lower urinary tract symptoms (LUTS), elevated prostate-specific antigen (PSA), negative prostate biopsy and clinically confirmed chronic non-bacterial prostatitis. The results of the present trial are the first firm evidence that cranberries may ameliorate LUTS, independent of benign prostatic hyperplasia or C-reactive protein level.
  2. Wang CH et al. Cranberry-Containing Products for Prevention of Urinary Tract Infections in Susceptible Populations: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Arch Intern Med. 2012;172(13):988-996. Summary: The results of the present meta-analysis support that consumption of cranberry-containing products may protect against UTIs in certain populations.
  3. Luis A et al. Can Cranberries Contribute to Reduce the Incidence of Urinary Tract Infections? A Systematic Review with Meta-Analysis and Trial Sequential Analysis of Clinical Trials. The Journal of Urology. Volume 3 198. Issue 3. September 2017. Pages 614-621. Summary: The findings clearly showed the potential use of cranberries for the clinical condition of urinary tract infection. Cranberry products significantly reduced the incidence of urinary tract infections as indicated by the weighted risk ratio (0.6750, 95% CI 0.5516–0.7965, p < 0.0001). The results could be used by physicians to recommend cranberry ingestion to decrease the incidence of urinary tract infections, particularly in individuals with recurrent urinary tract infections. This would also reduce the administration of antibiotics, which could be beneficial since antibiotics can lead to the worldwide emergence of antibiotic resistant microorganisms.

  1. Chen P et al. Lycopene and Risk of Prostate Cancer. A Systematic Review and Meta-Analysis. Medicine (Baltimore). 2015 Aug;94(33): 31260. Summary: This study demonstrates that higher lycopene consumption/circulating concentration is associated with a lower risk of PCa.
  2. Lane JA et al. ProDiet: A Phase II Randomized Placebo-controlled Trial of Green Tea Catechins and Lycopene in Men at Increased Risk of Prostate Cancer. Cancer Pres Res. 2018 Nov;11(1): 687-696. Summary: This study aimed to establish the feasibility and acceptability of dietary modification in men at increased risk of prostate cancer. Men were invited with a PSA level of 2.0-2.95 ng/mL or 3.0-19.95 ng/mL with negative prostate biopsies. Randomization (3 × 3 factorial design) to daily green tea and lycopene: green tea drink (3 cups, unblinded) or capsules [blinded, 600 mg flavan-3-ol ()-epigallocatechin-3-gallate (EGCG) or placebo] and lycopene-rich foods (unblinded) or capsules (blinded, 15 mg lycopene or placebo) for 6 months. All interventions were acceptable and well tolerated although men preferred the capsules. Dietary prevention is acceptable to men at risk of prostate cancer. This intervention trial demonstrates that a chemoprevention clinical trial is feasible.
  3. Wang Y et al. Lycopene, tomato products and prostate cancer-specific mortality among men diagnosed with nonmetastatic prostate cancer in the Cancer Prevention Study II Nutrition Cohort. Int J Cancer. 2016 June 15;138 (12):2846-55. Summary: Among men with high-risk cancers (T3-T4 or Gleason score 8-10, or nodal involvement), consistently reporting lycopene intake ≥ median on both post diagnosis surveys was associated with lower prostate-cancer specific mortality.

  1. Sharma P et al. Pomegranate for Prevention and Treatment of Cancer: An Update. Molecules. 24 January 2017. Summary: This review summarizes preclinical and clinical studies highlighting the role of pomegranate in prevention and treatment of skin, breast, prostate, lung, and colon cancers.
  2. Vicinanza R et al. Pomegranate Juice Metabolites, Ellagic Acid and Urolithin A, Synergistically Inhibit Androgen-Independent Prostate Cancer Cell Growth via Distinct Effects on Cell Cycle Control and Apoptosis. Evidence Based Complementary and Alternative Medicine. 19 February 2013. Summary: This study describes how ellagitannins (ETs) from pomegranate juice (PJ) are bioactive polyphenols with chemopreventive potential against prostate cancer (PCa).
  3. Wang L et al. Cellular and molecular mechanisms of pomegranate juice-induced anti-metastatic effect on prostate cancer cells. Integr Biol. 2011 May 19. Summary: This study demonstrates how, in addition to causing cell death of hormone-refractory prostate cancer cells, pomegranate also increases cell adhesion and decreases cell migration of the cells that do not die.
  4. Chaves FM et al. Pomegranate Juice and Peel Extracts are Able to Inhibit Proliferation, Migration and Colony Formation of Prostate Cancer Cell Lines and Modulate the Akt/mTOR/S6K Signaling Pathway. Plant Foods Hum Nutr. 2020 March;75(1):54-62. Summary: This study presents evidence that both juice and isolated peel extracts from pomegranate fruit have important anti-cancer effects against prostate cancer cells, modulating the mTOR/S6K signaling pathway.
  5. Kroeger N et al. Pomegranate Extracts in the Management of Men's Urologic Health: Scientific Rationale and Preclinical and Clinical Data. Evid Based Complement Alternat Med. 2013 Mar 26. Abstract: Numerous micronutrients and polyphenols found in soy, green tea, and many fruits and vegetables have been described to impact diseases including erectile dysfunction, benign prostatic hyperplasia, and prostate cancer. However, oftentimes these reports lack both a scientific rationale and supportive evidence base. The efficacy of pomegranate, on the other hand, in the modulation of central biological processes like inflammation, hypoxia, and oxidative stress that are important in the pathogenesis of urological maladies has been robustly demonstrated in preclinical in vitro and in vivo studies. Moreover, clinical trials have further supported its use in the treatment of several diseases, in particular in the management of prostate cancer.
  6. Forest CP et al. Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction: a randomized, placebo-controlled, double-blind, crossover study. Int J Impot Res. Nov-Dec 2007;19(6):564-7. Abstract: This randomized-controlled trial examined the efficacy of wonderful variety pomegranate juice versus placebo in improving erections in 53 completed subjects with mild to moderate erectile dysfunction. The crossover design consisted of two 4-week treatment periods separated by a 2-week washout. Efficacy was assessed using International Index of Erectile Function (IIEF) and Global Assessment Questionnaires (GAQ). Of the 42 subjects who demonstrated improvement in GAQ scores after beverage consumption, 25 reported improvement after drinking pomegranate juice. Further, 17 subjects showed preference of one beverage to the other. Subjects were more likely to have improved scores when pomegranate juice was consumed (P=0.058).
  7. Jeranka JS. Therapeutic Applications of Pomegranate (Punica granatum L.): A Review. Alternative Medicine Review: A Journal of Clinical Therapeutic, July 2008,13(2):128-44. Abstract: In addition to its ancient historical uses, pomegranate is used in several systems of medicine for a variety of ailments. In the past decade, numerous studies on the antioxidant, anticarcinogenic, and anti-inflammatory properties of pomegranate constituents have been published, focusing on treatment and prevention of cancer, cardiovascular disease, diabetes, dental conditions, erectile dysfunction, bacterial infections and antibiotic resistance, and ultraviolet radiation-induced skin damage. Other potential applications include infant brain ischemia, male infertility, Alzheimer's disease, arthritis, and obesity.
  8. Gur S et al. Characterisation of pomegranate juice effects on human corpus cavernosum. Andrologia 2017 Oct;49(8). Abstract: This study evaluates the molecular characterisation and confirmation of POM's action on human corpus cavernosum (HCC) obtained from patients (n = 16) undergoing penile prosthesis implantation. We conclude that POM induced marked relaxation of HCC via: (i) nNOS stimulation, and (ii) downstream relaxation stimulated by nNOS and cGMP and bypassing the NO and PDE5. This action provides a rationale for the therapeutic or preventative use of POM in men with erectile dysfunction who do not respond well to PDE5 inhibitors.
  9. Azadzoi K et al. Oxidative stress in arteriogenic erectile dysfunction: prophylactic role of antioxidants. J Urol. 2005 Jul;174(1):368-93. Abstract: Antioxidant activity of known antioxidant beverages, such as pomegranate juice (PJ), red wine, blueberry juice, cranberry juice, orange juice and green tea, was examined spectrophotometrically. PJ demonstrated the highest free radical scavenging capacity. Antioxidant therapy may be a useful prophylactic tool for preventing smooth muscle dysfunction and fibrosis in ED.
  10. Deng Y et al. The extract from Punica granatum (pomegranate) peel induces apoptosis and impairs metastasis in prostate cancer cells. Biomed Pharmacother. 2017 Se9;93:976-984. Abstract: This study aimed to investigate the effects of pomegranate peel extract (PoPx) on the apoptosis and metastasis of prostate cancer cells and the related mechanism. They found that PoPx showed growth inhibition on prostate cancer cells. Nuclei morphological and flow cytometer (FCM) analysis indicated that PoPx could induce prostate cancer apoptosis. Wound healing assay and transwell migration and invasion assay implied that PoPx has the potential to inhibit migration and invasion, two critical steps in prostate cancer metastasis. Downregulation of MMP2/MMP9 and upregulation of TIMP2 showed accordance with the inhibition of migration and invasion. In summary, the present data showed that PoPx could be a promising drug candidate to treat prostate cancer, showing us a better way to develop novel drugs from natural compounds.
  11. Bassiri-Jahromi S. Punica granatum (Pomegranate) activity in health promotion and cancer prevention. Oncol Res. 2018 Jan 30;12(1):345. Abstract: The available data suggest that Punica granatum (pomegranate) might be used in the control and potential therapeutic for some disease conditions and benefits human health status. This review summarizes in vitro, in vivo and clinical trial studies highlighting the pomegranate role in prevent and treatment of breast, prostate, lung, colon, skin and hepatocellular cell cancers.
  12. Chrubasik-Hausman S et al. Pomegranate juice and prostate cancer: importance of the characterisation of the active principle. Phytoter Res. 2014 Nov;28(11):1676-8. Abstract: Two exploratory clinical studies investigating proprietary pomegranate products showed a trend of effectiveness in increasing prostate-specific antigen doubling time in patients with prostate cancer. A recent clinical study did not support these results. We therefore analysed a lot of the marketed pomegranate blend for co-active pomegranate compounds. The results show that the co-active compounds in the daily dose of the pomegranate blend were far below those previously tested and that the photometric assessment is not reliable for the standardisation of study medications. Not pomegranate but the low amount of co-active compounds in the proprietary pomegranate blend was responsible for its clinical ineffectiveness.
  13. Wang L et al. Pomegranate and Its Components as Alternative Treatment for Prostate Cancer Int J Mol Sci. 2014 Sep; 15 (9):14949-14966. Abstract: Recent research has shown that pomegranate juice (PJ) and/or pomegranate extracts (PE) significantly inhibit the growth of prostate cancer cells in culture. In preclinical murine models, PJ and/or PE inhibit growth and angiogenesis of prostate tumors. More recently, it has been shown that three components of PJ, luteolin, ellagic acid and punicic acid together, have similar inhibitory effects on prostate cancer growth, angiogenesis and metastasis. Results from clinical trials are also promising. PJ and/or PE significantly prolonged the prostate specific antigen (PSA) doubling time in patients with prostate cancer.
  14. Amri Z et al. Growth Inhibitory and Pro-Apoptotic Effects of Ornamental Pomegranate Extracts in Du145 Human Prostate Cancer Cells. Nutrition and Cancer. Volume 72. 2020. Issue 6. Abstract: This study was aimed to investigate the influence of dwarf pomegranate extracts (peel, juice, and seeds oil) on the proliferation and apoptosis of human prostate androgen-independent cell line DU145. The three tested extracts exhibited a dose-response cytotoxic effect and antiproliferative action on DU145 cell line and induce morphological changes. The three extracts could also induce prostate cancer cell apoptosis by an increase of DNA fragmentation, PARP cleavage, and inhibition of the COX-2 expression. The strongest pro-apoptotic effect was shown after peel treatment.

Customer Reviews
4.8 Based on 17 Reviews
5 ★
94% 
16
4 ★
0% 
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3 ★
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2 ★
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Filter Reviews:
WA
01/19/2024
William A.
United States

Great product

Product works well I tend to retain water and I feel this product helps me urinate more often and gives me a stronger stream looking forward to continued improvement from use

KE
12/15/2023
Kenny E.
United States United States

Good Product

Good. I have been using for a couple years now.

RM
12/13/2023
Robert M.
United States United States

Unbelievable Results

While I can't exactly prove it for sure, I have noticed a decrease in hard plaque build up in my blood vessels in my nether regions since stepping up my dosing of P-Well. My urologist says that shouldn't happen, but my own body is my proof. Thanks for making great supplements that work. I recommend Biotest to all my friends.

A T Nation Biotest Store Customer
JG
11/30/2023
Julio G.
United States United States

Love it

Great product for prostate needs

SB
08/01/2023
Seth B.
United States United States

P-Well Works

This seems to be helping my libido - love it!

RP
07/25/2023
Ronald P.
United States United States

Great product

Does what its supposed to do!

AL
07/07/2023
Alisa L.
United States United States

Husband AND wife… both believers!

Thankful my husband sent me a link to P Well and it’s benefits for women. I was honestly skeptical but wanted us both to try it as we are approaching 50. And I’m glad I was willing to try. We both have noted a significant improvement in urinary urgency and being able to “hold it” when needed much easier. He also reports feeling like he actually is able to empty his bladder and with increased flow ease. I have also not had any issues with urinary leakage since starting P Well. I was starting to think I needed a light incontinence pad most days for the 1-2 a week accidental leakage. No more. Can even sneeze and jump around without worry of peeing my pants! We are sold. I’m telling all my friends about it and it’s on auto ship!

RP
06/16/2023
Ronald P.
United States United States

Awesome product

Does what it says

TF
06/14/2023
Thomas F.
United States United States

More like P-hard

This is great stuff. It has a subtle effect for me, but I like taking it. After a few weeks I notice things are a touch stiffer and much more easily stiffened. Nothing crazy but I feel it is noticeable. And I hope that it does have long term effects. There will be no way to tell until (knock on wood) I'm an old, hard man.

J
05/02/2023
JRB
United States United States

Good Stuff

No more night time visits to the bathroom. I've been taking saw palmetto & finasteride, but I would still have nightly occurrences. Not any more!

RW
04/29/2023
Roger W.
United States United States

P-well

Have only used for a week so too early to tell. Will update after another week.

SB
04/29/2023
Seth B.
United States United States

Helped my libido

Surprisingly noticeable and positive effect on my libido. My wife noticed it too!

TS
04/20/2023
Thomas S.
United States United States

P-Well (Da Best)

Great product, have used for years. Improved prostate health ALL around. Strongly recommend for those 60 plus dealing with body changes. Give it time to work, at least (2) bottles...

AB
02/02/2023
ANTHONY B.
United States United States

TONYFRUITS

HIS WORKS GREAT

GB
12/14/2022
Glenn B.
United States United States

Helped to stop recurring UTI problems

Two times in back to back years I had bouts with Urinary Tract Infection. The first time it was very painful. I mean gripping anything you could hang onto while urinating painful. I made an appointment with my doctor, received antibiotics, and soon everything was fine. The second time occurred during the pandemic and making an appointment with a doctor or urgent care facility took days to happen. Fortunately, during this bout I had started taking P-Well. Though it is no cure for UTI it did make the symptoms less severe until I could be seen by a doctor. I have continued to take P-Well and have had no recurrence of an infection for two years now.

12/08/2022
Anonymous
Canada Canada

P-Well

Am using this product for long-term health (specifically kidney health). Pleased with results (lab work) to date.

TD
08/30/2022
TJ D.
United States United States

Amazing

This stuff works wonders. I used to have pains in my lower abdomen because I’d have to urinate so bad after a night of sleep. I no longer have those pains. I also have noticed my erections are a lot better than they used to be. The only thing I switched up was using this product. This is legit and I recommend this to everyone and anyone that struggles with the same issues.

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.