Rez-V High Absorption Resveratrol
Rez-V High Absorption Resveratrol
Rez-V High Absorption Resveratrol

Rez-V High Absorption Resveratrol

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Resveratrol is a natural polyphenol found in small amounts in red grapes and wine. Studies show resveratrol is a highly effective estrogen blocker and a potent aromatase inhibitor, minimizing negative estrogen effects and maximizing natural testosterone. Resveratrol also provides significant cardiovascular and neurological health benefits and activates fat burning. Two Rez-V™ softgels contain 600 mg of active pure trans-resveratrol, the type and amount required for an effective dose of this powerful science-backed ingredient.*


  1. Controls estrogen in two ways*
  2. Acts as a potent estrogen blocker*
  3. Acts as a potent aromatase inhibitor*
  4. Increases natural testosterone levels*
  5. Protects against man-made environmental estrogens that lower testosterone*
  6. Stimulates fat burning*
  7. Promotes cardiovascular health*
  8. Exhibits prostate protectant effects, liver protective effects, and anti-aging effects*

Control Estrogen to Live Better and Look Better*

Active men naturally want high testosterone. "High-normal" testosterone gives you an advantage in building and maintaining a lean, muscular, hi-performance body – and it generally makes you feel great.

The trouble is, some testosterone naturally converts into estrogen through aromatization. And with elevated estrogen, you can easily gain fat, bloat with excess water, have a tough time even maintaining muscle mass and strength, and even impact your prostate health. Too much estrogen also signals the body, though negative feedback, to produce less testosterone.

While men need some estrogen to maintain cardiovascular health, it can cause many problems if it gets out of control.

Man-Made Estrogens Are Everywhere

Adding to the estrogen problem, many chemicals in the environment mimic estrogen. They're called xenoestrogens, and they're everywhere: in plastic bottles and bowls, shampoos, detergents, even toothpaste. Xenoestrogens are unavoidable and will find their way into your body every day.

Resveratrol: Estrogen Blocker

Resveratrol acts as a potent estrogen antagonist (blocker) while also acting as a "healthy" (weak) agonist in cardiovascular tissues (similar to the drugs clomiphene and tamoxifen). As a blocker, resveratrol occupies estrogen receptor sites, or biological "parking lots," so xenoestrogens can't "park" and activate the receptor – no activation means no negative effects.

Resveratrol: Aromatase Inhibitor

In higher concentrations, resveratrol also acts as an aromatase inhibitor, preventing the body from converting testosterone into estrogen, with the bonus of increasing testosterone. Resveratrol inhibits aromatase by reducing its expression and by binding to it. And, unlike pharmaceutical aromatase inhibitors, resveratrol doesn't decrease blood vessel function; it seems to improve it.*

Resveratrol: Fat Burner

Calorie deprivation activates a protein called SIRT1, which inhibits PPAR-gamma activity and causes your body to burn fat. Resveratrol activates this very same SIRT1 protein without you needing to diet excessively.*

Resveratrol: Supplement for Heath

Additionally, there's overwhelming scientific evidence that resveratrol provides potent cardiovascular benefits, anti-aging effects, and positive neurological effects. Many of these benefits stem from anti-oxidative and anti-inflammatory actions and gene modulation.*

Controls Estrogen in 2 Ways*

Rez-V High Absorption Resveratrol Benefit

Blocks Excessive
Estrogen Activity*

Rez-V High Absorption Resveratrol Benefit

Boosts Natural

Rez-V High Absorption Resveratrol Benefit

Cardiovascular Health*

  1. Juan ME et al. Trans-Resveratrol, a natural antioxidant from grapes, Increases sperm output in healthy rats. J Nutr. 2005 Apr;135(4):757-60.
  2. Bhat KP et al. Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models. Cancer Res. 2001 Oct 15;61(20):7456-63.
  3. Henry LA et al. Resveratrol: phytoestrogen effects on reproductive physiology and behavior in female rats. Horm Behav. 2002 Mar;41(2):220-8.
  4. Matsumura A et al. Comparative study of oestrogenic properties of eight phytoestrogens in MCF7 human breast cancer cells. J Steroid Biochem Mol Biol. 2005 Apr;94(5):431-43.
  5. Bowers JL et al. Resveratrol acts as a mixed agonist/antagonist for estrogen receptors alpha and beta. Endocrinology. 2000 Oct;141(10):3657-67.
  6. Lu R et al. Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells. J Cell Physiol. 1999 Jun;179(3):297-304.
  7. Turner RT et al. Is resveratrol an estrogen agonist in growing rats? Endocrinology. 1999 Jan;140(1):50-4.
  8. Bhat KP et al. Resveratrol exhibits cytostatic and antiestrogenic properties with human endometrial adenocarcinoma (Ishikawa) cells. Cancer Res. 2001 Aug 15;61(16):6137-44.
  9. Wang Y et al. The Red Wine Polyphenol Resveratrol Displays BI-Level Inhibition on Aromatase in Breast Cancer Cells. Toxicol Sci. 2006 Apr 11
  10. Wallerath T et al. A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase. Nitric Oxide. 2005 Mar;12(2):97-104.
  11. Lekakis J et al. Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease. Eur J Cardiovasc Prev Rehabil. 2005 Dec;12(6):596-600.
  12. Buluc M et al. Resveratrol decreases calcium sensitivity of vascular smooth muscle and enhances cytosolic calcium increase in endothelium. Vascul Pharmacol. 2006 Apr;44(4):231-7.
  13. Labinskyy N et al. Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen. Curr Med Chem. 2006;13(9):989-96.
  14. Bhat KPL et al. Biological effects of resveratrol. Antioxid Redox Signal. 2001 Dec;3(6):1041-64.
  15. Bradamante S, et al. Cardiovascular protective effects of resveratrol. Cardiovasc Drug Rev. 2004 Fall;22(3):169-88.
  16. de la Lastra CA et al. Resveratrol as an anti-inflammatory and anti-aging agent: mechanisms and clinical implications. Mol Nutr Food Res. 2005 May;49(5):405-30. doi: 10.1002/mnfr.200500022.
  17. Delmas D et al. Resveratrol: preventing properties against vascular alterations and ageing. Mol Nutr Food Res. 2005 May;49(5):377-95.
  18. Valenzano DR et al. Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate. Curr Biol. 2006 Feb 7;16(3):296-300.
  19. Marambaud P et al. Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J. Biol. Chem 2005 Nov;280(45): 37377-37382
  20. Molnar V et al. Plant-derived anti-inflammatory compounds affect MIF tautomerase activity. Int Immunopharmacol. 2005 May;5(5):849-56.
  21. Elmali N et al. Effect of resveratrol in experimental osteoarthritis in rabbits. Inflamm Res. 2005 Apr;54(4):158-62.
  22. Kopp P. Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of the 'French paradox'? Eur J Endocrinol. 1998 Jun;138(6):619-20.
  23. Constant J. Alcohol, ischemic heart disease, and the French paradox. Coron. Artery Dis. 1997; 8:645 – 649.
  24. Das D K et al. Cardioprotection of red wine: role of polyphenolic antioxidants. Drugs Exp Clin Res. 1999;25(2-3):115-20.
  25. Soleas GJ, Diamandis EP, Goldberg DM. The world of resveratrol. Adv Exp Med Biol. 2001;492:159-82.
  26. Wyke SM, Tisdale MJ. Induction of protein degradation in skeletal muscle by a phorbol ester involves upregulation of the ubiquitin-proteasome proteolytic pathway. 2006 May;78(25):2898-2910
  27. Tisdale MJ. The ubiquitin-proteasome pathway as a therapeutic target for muscle wasting. J Support Oncol. 2005 May-Jun;3(3):209-17.
  28. Wyke SM et al. Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation. Br J Cancer. 2004 Nov 1;91(9):1742-50.
  29. Borra MT et al. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem. 2005 Apr 29;280(17):17187-95.
  30. Picard F, et al. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature. 2004 Jun 17;429(6993):771-6.
  31. Wolf G. Calorie restriction increases life span: a molecular mechanism. Nutr Rev. 2006 Feb;64(2 Pt 1):89-92.
  32. Ingram DK et al. Calorie restriction mimetics: an emerging research field. Aging Cell. 2006 Apr;5(2):97-108.
  33. Roth GS et al. Caloric restriction mimetics: the next phase. Ann N Y Acad Sci. 2005 Dec;1057:365-71.
  34. Tian WX. Inhibition of fatty acid synthase by polyphenols. Curr Med Chem. 2006;13(8):967-77.
  35. Kasdallah-Grissa A, et al. Protective effect of resveratrol on ethanol-induced lipid peroxidation in rats. Alcohol Alcohol. 2006 May-Jun;41(3):236-9
  36. Sener G et al. Protective effects of resveratrol against acetaminophen-induced toxicity in mice. Hepatol Res. 2006 Apr 1; E-Published Ahead of Print
  37. Docherty JJ et al. Effect of resveratrol on herpes simplex virus vaginal infection in the mouse. Antiviral Res. 2005 Sep;67(3):155-62.
  38. Jung HJ et al. Fungicidal effect of resveratrol on human infectious fungi. Arch Pharm Res. 2005 May;28(5):557-60.
  39. Palamara AT et al. Inhibition of influenza A virus replication by resveratrol. J Infect Dis. 2005 May 15;191(10):1719-29.
  40. Yoo KM et al. Potent Inhibitory Effects of Resveratrol Derivatives on Progression of Prostate Cancer Cells. Arch Pharm (Weinheim). 2006 Apr 18;339(5):238-241
  41. Jones SB et al. Resveratrol-induced gene expression profiles in human prostate cancer cells. Cancer Epidemiol Biomarkers Prev. 2005 Mar;14(3):596-604.
  42. Scifo C et al. Resveratrol and propolis as necrosis or apoptosis inducers in human prostate carcinoma cells. Oncol Res. 2004;14(9):415-26.
  43. Kim YA et al. Antiproliferative effect of resveratrol in human prostate carcinoma cells. J Med Food. 2003 Winter;6(4):273-80.
  44. Stewart JR et al. Resveratrol: a candidate nutritional substance for prostate cancer prevention. J Nutr. 2003 Jul;133(7 Suppl):2440S-2443S.
  45. Ratan HL et al. Resveratrol – a prostate cancer chemopreventive agent? Urol Oncol. 2002 Nov-Dec;7(6):223-7.
  46. Aggarwal BB, et al. Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Res. 2004 Sep-Oct;24(5A):2783-840.
  47. Aziz MH et al. Cancer chemoprevention by resveratrol: in vitro and in vivo studies and the underlying mechanisms (review). Int J Oncol. 2003 Jul;23(1):17-28.
  48. Delmas D et al. Resveratrol as a chemopreventive agent: a promising molecule for fighting cancer. Curr Drug Targets. 2006 Apr;7(4):423-42.

Customer Reviews
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Filter Reviews:
Derek A.
United States


I take this most everyday. Great quality and value for a supplement that works!

Charles G.
United States United States


I’ve used this in the past with great results. That’s why I bought it again. I need to subscribe to get this on the regular along with carbolin-19.

Charles R.
United States United States

I think it has really helped with estrogen control

gregory w.
United States United States

By What Measure 2.0?

What are you expecting. "I feel 20 years younger." "I've lost 3% body fat." "I added 40 pounds to my bench press." "Everyone says how great I look." Is there a blood test to show me what (if anything) this stuff is doing?

Curtis W.
United States United States

Well worth getting

This is perhaps the best resveratrol supplement I've ever used. Not watered down, not just one of twenty-five different things in a formulation, just a well designed and effective product.

gregory w.
United States United States

By What Measure?

I trust there is a benefit to this supplement, and it is what it claims to be. There is however, no definitive, measurable result that can verify its effectiveness. Had I engaged a medical blood laboratory for testing before and after starting use of this supplement, I might be able to offer some kind of objective evaluation of my experience. Absent that, I'll enjoy the emotional placebo effect that this wonderful supplement provides me.

Dustin m.
United States United States


Good product, don't really notice much of a difference in the way I feel, but take it for the overall health benefits

John v.
United States United States

Gets The Job Done

My lab results indicate that since I began taking REZ-V my estrogen levels have dropped dramatically. For that reason, I continue to take it.

Frank L.
United States United States

Real Deal

I love using Rez-V as an older lifter and it will remain a staple of my supplements.

Thomas M.
United States United States


I've been using it for a month. What am I supposed to notice as far as anything as I haven't noticed any effect on me

James W.
United Arab Emirates United Arab Emirates

Best Resveratrol on market, w a small caution

Wonderful! You get what you pay for, and Biotest products are always excellent. Warning: in the case of Rez-V, all major studies on resveratrol require 1000-2000 mg, meaning doubling or tripling any resveratrol bottle recommended serving sizes as a minimum, if not more. Having said that, it really is worth it, and ALL resveratrol on the market knowingly underdoses their recommended serving size, or else the manufacturers would scare off consumers with the absurd sticker-shock quantities required. The reason I splurge/go through two bottles a month of Biotest's Rez-V is their high-efficacy delivery. I'm a lean 230 lbs guy, and studies all use 1000-2000 on normal people for proven results. But with the efficacy of Rez-V I feel confident going with the minimum true 1000-1200 effective single dose (5-6 capsules) for me. With any other company, I would definitely be shooting for the 2000mg range or more, typically meaning 10-14 pills a day. Only using 6 capsules a day of Rez-V seems far more reasonable to me than would I would need to do with any other brand. As former triathlete, NPC Heavyweight National Level Bodybuilder, and a longevity Biohacker, I believe two bottles a month is enough for almost anyone, even me. Good luck!

John v.
United States United States

Fantastic Product!

In two months, this anti-estrogen supplement reduced my estrogen level remarkably. My doctor asked for information on it to pass on to his other patients.

Steve S.
United States United States

Positively benefits

I added it because I believe it’s/ positive plus in workouts

jan l.
United States United States

Review for somebody from Dominican republic

I think it was good I had a nice discountt on my 5 Rez-V purchase. But I have a problem with the delivery. It was on time but it was hold in my locker because it didn't have a code of membership I had to provide. Next time I'll be more expecific.

T Nation Biotest Store Rez-V High Absorption Resveratrol Review
Patrick E.
United States United States


Subjectively, I always feel better - a bit stronger, more flexible, better 'emptying' experience when doing 'number one'. Good value - I get a month's supply at a price I can afford (on auto ship or coupon) and I 'feel' that it is doing what it claims. Disclosure: Nearly 60 years old and keeping' it up!

John L.
United States United States


At age 72, I'm concerned with my T level as well as my E level. Taking REZ-V from BIOTEST not only keeps both in balance but helps with my prostate function. If you're not taking this supplement, you need to LEARN WHY YOU NEED IT!

John L.
United States United States


At age 72, I'm concerned with my T level as well as my E level. Taking REZ-V from BIOTEST not only keeps both in balance but helps with my prostate function. If you're not taking this supplement, you need to LEARN WHY YOU NEED IT!

Kevin D.
United States United States

Amazing product

I was having an issue with estrogen, I tried several other products that helped a little, within a week of using REZ-Z my levels dropped to normal, I am on low dose TRT, this was the only thing that worked. I recommend this product to everyone I know.

David B.
United States United States

Not bad for an old guy

At 67 my test and estradiol was out of whack... last blood test my testosterone was almost 400 and estradiol in the 30's... think it's working pretty good!

United States United States

Rez-V Review

Can’t really tell. Will keep taking it for the reported benefits. No actual physical feedback to judge.

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.