Finally... A Good Night's Sleep
Nothing aids performance, physical or mental, more than a good night's sleep. Conversely, nothing hurts performance more than a poor night's sleep. Worse, lack of sleep kills the ability to enjoy life. It saps us of our strength, our vitality.
For years, doctors have told us that sleeplessness results from depression, neurosis, or some other underlying psychological pathology. But there's evidence to suggest that we've got it backward, that sleeplessness leads to depression, in addition to alcoholism, emotional instability, and other mental problems!
While surveys suggest that 10 to 15 percent of the U.S. population suffers from chronic insomnia, personal experience and anecdotal data lead me to believe that occasional sleeplessness plagues at least half of the population. The causes are largely unknown, although there's some indication that it might even be genetic.
Regardless of the cause, sleeplessness takes its toll in the gym, in business, and in health. People who suffer from sleeplessness have statistically more visits to the doctor (because they're at the mercy of every passing illness), more hospitalization, and more accidents on the job and on the road.
Obviously, rest is crucial. We all know it. Now it's time we applied the inestimable creativity of Biotest researchers to addressing it. Enter the latest Biotest product. Enter blissful rest without a sleep hangover. Enter calmness without loss of strength or focus.
Z-12™ – The Ultimate, Non-Addictive Sleep Formula
Z-12™ provides a full night's sleep without the sleep "hangover" associated with virtually all other prescription or non-prescription sleep aids.
Z-12™ is also useful to people who might not generally have trouble sleeping, but who might occasionally need a guaranteed good night's sleep, like the night before an exam, a job interview, or athletic meet. And Travelers might find it useful, too, in overcoming the first-night insomnia that often afflicts those who sleep in beds they're not accustomed to.
The typical experience with Z-12™ results in falling into a deep, restful, uninterrupted sleep within 15 minutes of taking two capsules at bedtime, and waking up the next morning entirely refreshed without the least bit of grogginess.
The main workhorse in Z-12 is PhGABA. The compound is a derivative of the inhibitory neurotransmitter GABA. When we're stressed, our brains experience an uninterrupted flow of stimulatory neurotransmitters and this causes restlessness, irritability, and insomnia.
GABA, and compounds related to it like the PhGABA in Biotest's Z-12, inhibit the flow of these stimulatory neurotransmitters, thereby allowing the brain and body to relax. PhGABA not only acts like GABA, but it also causes the release of GABA for a one-two sleep-inducing punch.
There have been a ton of studies on PhGABA and many of them have compared the compound to Valium, which has pronounced anxiolytic (anxiety-reducing) properties, and the nootropic compound piracetam, which has weaker anxiolytic properties.
In parts of Europe, the compound is used to treat post-traumatic stress disorder, stuttering, and of course, insomnia. Furthermore, double-blind studies found the compound to increase intellectual function, improve physical strength, and reduce fatigue in neurotic patients.While it's not commonly known as a performance-enhancing supplement, PhGABA has been shown to improve work capacity in humans, along with increasing the performance of animals on swim tests.
PhGABA is an amazingly safe compound. Unlike many compounds, it seems to have no known negative side effects. In fact, it's even been found to have cardioprotective properties. The plasma half-life of a 250-mg dose of PhGABA is 5.3 hours, and most of the compound is excreted unchanged.
5-HTP (5-hydroxytryptophan) is a naturally occurring amino acid that's a precursor to the neurotransmitter serotonin (5-hydroxytryptamine), which is implicated in sleep and general feelings of well-being. When blood levels of 5-HTP are high, it causes the brain's serotonin producing neurons to increase production.
Furthermore, we believe that 5-HTP, in addition to being serotonergic, actually "resets" (normalizes) the hypothalamic-pituitary-adrenal (HPA) axis. In addition to helping the body adapt better to stress, this resetting effect also helps PhGABA and L-theanine to keep on working without allowing the user to develop tolerance.
L-Theanine is an amino acid found in green tea. Due to it promoting brain alpha-wave function, L-theanine facilitates a calm, relaxed-mental state. Animal studies suggest it increases brain serotonin and GABA levels, along with perhaps being both a neuroprotective agent and a cognitive enhancing agent.
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RECOMMENDED USE: Take 2-4 capsules on an empty stomach 30 minutes prior to bedtime, or whenever desiring a calm, relaxed state. To determine the ideal dose, begin with two capsules per day and increase by one capsule per day (up to a maximum of four) until achieving the desired effect. Never exceed four capsules per day. To keep the body sensitive to the effects, do not take more than once per day.
WARNING: Do not take with alcohol. Do not take if you are pregnant or breast feeding, elderly or under the age of 18, chronically ill, or taking any prescription or over-the-counter medicines, including but not limited to antidepressants (such as MAO inhibitors and serotonin reuptake inhibitors), allergy medications, and medications for cardiovascular conditions. KEEP OUT OF REACH OF CHILDREN.