Finally... A Good Night's Sleep
Nothing aids performance, physical or mental, more than a good night's sleep. Conversely, nothing hurts performance more than a poor night's sleep. Worse, lack of sleep kills the ability to enjoy life. It saps us of our strength, our vitality.
For years, doctors have told us that sleeplessness results from depression, neurosis, or some other underlying psychological pathology. But there's evidence to suggest that we've got it backward!
While surveys suggest that 10 to 15 percent of the U.S. population suffers from significant sleep problems, personal experience and anecdotal data lead me to believe that occasional sleeplessness plagues at least half of the population. The causes are largely unknown, although there's some indication that it might even be genetic.
Regardless of the cause, sleeplessness takes its toll in the gym, in business, and in health. People who suffer from sleeplessness have statistically more visits to the doctor, more hospitalization, and more accidents on the job and on the road.
Obviously, rest is crucial. We all know it. Now it's time we applied the inestimable creativity of Biotest researchers to addressing it. Enter the latest Biotest product. Enter blissful rest without a sleep hangover. Enter calmness without loss of strength or focus.
Z-12™ – The Ultimate, Non-Addictive Sleep Formula
Z-12™ provides a full night's sleep without the sleep "hangover" associated with virtually all sleep aids.
Z-12™ is useful to people who might not generally have trouble sleeping, but who might occasionally need a guaranteed good night's sleep, like the night before an exam, a job interview, or athletic meet. And Travelers might find it useful, too, in overcoming the first-night restlessness that often afflicts those who sleep in beds they're not accustomed to.
The typical experience with Z-12™ results in falling into a deep, restful, uninterrupted sleep within 15 minutes of taking two capsules at bedtime, and waking up the next morning entirely refreshed without the least bit of grogginess.
The main workhorse in Z-12 is PhGABA. The compound is a derivative of the inhibitory neurotransmitter GABA. When we're stressed, our brains experience an uninterrupted flow of stimulatory neurotransmitters and this causes restlessness, and irritability.
GABA, and compounds related to it like the PhGABA in Biotest's Z-12, inhibit the flow of these stimulatory neurotransmitters, thereby allowing the brain and body to relax. PhGABA not only acts like GABA, but it also causes the release of GABA for a one-two sleep-inducing punch.
There have been a ton of studies on PhGABA and its effects on relaxation.
Furthermore, double-blind studies found the compound to increase intellectual function, improve physical strength, and reduce fatigue in neurotic patients. While it's not commonly known as a performance-enhancing supplement, PhGABA has been shown to improve work capacity in humans, along with increasing the performance of animals on swim tests.
PhGABA is an amazingly safe compound. Unlike many compounds, it seems to have no known negative side effects. In fact, it's even been found to have cardioprotective properties. The plasma half-life of a 250-mg dose of PhGABA is 5.3 hours, and most of the compound is excreted unchanged.
5-HTP (5-hydroxytryptophan) is a naturally occurring amino acid that's a precursor to the neurotransmitter serotonin (5-hydroxytryptamine), which is implicated in sleep and general feelings of well-being. When blood levels of 5-HTP are high, it causes the brain's serotonin producing neurons to increase production.
Furthermore, we believe that 5-HTP, in addition to being serotonergic, actually "resets" (normalizes) the hypothalamic-pituitary-adrenal (HPA) axis. In addition to helping the body adapt better to stress, this resetting effect also helps PhGABA and L-theanine to keep on working without allowing the user to develop tolerance.
L-Theanine is an amino acid found in green tea. Due to it promoting brain alpha-wave function, L-theanine facilitates a calm, relaxed-mental state. Animal studies suggest it increases brain serotonin and GABA levels, along with perhaps being both a neuroprotective agent and a cognitive enhancing agent.
CNS Drug Rev. 2001 Winter;7(4):471-81. Phenibut: a tranquilizer and nootropic drug. Lapin I.
Am J Physiol Gastrointest Liver Physiol. 2001 Aug;281(2):G311-5. Receptors and transmission in the brain-gut axis: potential for novel therapies. IV. GABA(B) receptors in the brain-esophageal axis. Blackshaw LA.
Farmakol Toksikol. 1985 Jul-Aug;48(4). Differences and similarity in the interaction of fenibut, baclofen, and diazepam with phenylethylamine. Lapin IP.
Pavlov J Biol Sci. 1986 Oct-Dec21(4):129-40. On neurotransmitter mechanisms of reinforcement and internal inhibition. Shulgina GI.
Farmakol Toksikol. 1989 Jul-Aug;52(4):37-9. Effect of fenibut on seduxen on fetal development in the second half of pregnancy. Filimonov, VG, et al.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Disclaimer: Individual results may vary.